hypnotic effect of rosa damascena in mice
نویسندگان
چکیده
rosa damascena (rosaceae) has been found to act on central nervous system including the brain. several studies confirm that rosa damascena inhibits the reactivity of the hypothalamus and pituitary systems in rat and can suppress the reactivity of central nervous system. in traditional medicine the hypnotic effect of rose is also suggested. in the present study hypnotic effect of ethanolic, aqueous and chloroformic extracts of rosa damascena was investigated in mice. hypnotic method was based on potentiation of pentobarbital induced sleeping time by extracts. three doses of extracts (100, 500 and 1000 mg/kg) were injected intraperitoneally in comparison with diazepam (3 mg/kg) as the positive control and saline as the negative control. thirty min after injection of extracts, pentobarbital (30 mg/kg) was injected and any increase in the sleeping time due to the extracts was recorded. results showed that the ethanolic and aqueous extracts in doses of 500 and 1000 mg/kg significantly increased the pentobarbital induced sleeping time (p<0.001, compared to the negative control), which was comparable to diazepam. the chloroformic extract showed no hypnotic effect.
منابع مشابه
Hypnotic Effect of Rosa damascena in Mice
Rosa damascena (Rosaceae) has been found to act on central nervous system including the brain. Several studies confirm that Rosa damascena inhibits the reactivity of the hypothalamus and pituitary systems in rat and can suppress the reactivity of central nervous system. In traditional medicine the hypnotic effect of rose is also suggested. In the present study hypnotic effect of ethanolic, aque...
متن کاملHypnotic Effect of Rosa damascena in Mice
Rosa damascena (Rosaceae) has been found to act on central nervous system including the brain. Several studies confirm that Rosa damascena inhibits the reactivity of the hypothalamus and pituitary systems in rat and can suppress the reactivity of central nervous system. In traditional medicine the hypnotic effect of rose is also suggested. In the present study hypnotic effect of ethanolic, aque...
متن کاملComparative Hypnotic Effect of Rosa damascena Fractions and Diazepam in Mice
Rosa damascena has been found to act on central nervous system including the brain. Several studies confirm that R. damascena inhibits the activity of the hypothalamus and pituitary systems in rat and can suppress the central nervous system. In traditional medicine hypnotic effect of Rose is also suggested. In this study, the hypnotic effect of the ethanol crude extract of R. damascena and its ...
متن کاملComparative Hypnotic Effect of Rosa damascena Fractions and Diazepam in Mice
Rosa damascena has been found to act on central nervous system including the brain. Several studies confirm that R. damascena inhibits the activity of the hypothalamus and pituitary systems in rat and can suppress the central nervous system. In traditional medicine hypnotic effect of Rose is also suggested. In this study, the hypnotic effect of the ethanol crude extract of R. damascena and its ...
متن کاملcomparative hypnotic effect of rosa damascena fractions and diazepam in mice
rosa damascena has been found to act on central nervous system including the brain. several studies confirm that r. damascena inhibits the activity of the hypothalamus and pituitary systems in rat and can suppress the central nervous system. in traditional medicine hypnotic effect of rose is also suggested. in this study, the hypnotic effect of the ethanol crude extract of r. damascena and its ...
متن کاملPotentiation of pentobarbital hypnosis by Rosa damascena in mice.
Rosa damascena has been found to act on central nervous system including brain. It inhibits the reactivity of the hypothalamous and pituitary systems in rat. In traditional medicine hypnotic effect of Rose is also suggested. In the present study hypnotic effect of ethanolic, aqueous and chloroformic extracts of R. damascena was investigated in mice. Hypnotic method was based on potentiation of ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of pharmaceutical researchجلد ۲۰۰۴، شماره ۷، صفحات ۱۸۱-۱۸۵
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023